Over time, especially after 40, but not always, the muscles around the mouth can pull the corners down, giving a sad appearance, also known as marionette lines.
The muscle primarily responsible for this is the DAO (depressor angularis oris).
By injecting 6 units into the DAO in total (3 units to each side), this can subtly relax the downturned corners of the mouth, so that the marionettes are less obvious. This treatment is best undertaken together with filler treatment (usually 1ml) for marionette lines as seen here:
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